Cosmic Injectables - Neuromodulators

(Botox, Dysport, Xeomin)

FDA-approved neuromodulators such as Botox, Dysport, and Xeomin are injectable treatments designed to temporarily reduce or eliminate moderate-to-severe dynamic wrinkles. These injectables are administered directly into the muscle beneath a wrinkle, relaxing the muscle and preventing it from contracting.

The injectables are derived from a neurotoxin produced by the bacterium Clostridium botulinum.

Applications for Neuromodulators

Medically, neuromodulators are used to treat conditions like migraines, TMJ (jaw clenching/grinding), excessive underarm sweating, cervical dystonia (which causes neck pain and abnormal head positioning), and muscle spasms.

Cosmetically, neuromodulator injections are commonly used to address:

  • Forehead wrinkles

  • Frown lines (between the brows)

  • Crow's feet

  • Nasal wrinkles

  • Neck bands

Injectable Procedure and Results

The neuromodulator is injected directly into the facial muscles causing wrinkles and lines, using a fine needle. While anesthesia is generally not required, some providers may numb the area with ice or topical numbing cream. Results are typically noticeable within a few days, and effects can last up to 4 months. Areas treated consistently may see longer-lasting results. It's important that injections are performed by qualified medical professionals.

Who Should Avoid Neuromodulator Treatment?

Certain individuals may not be suitable candidates for neuromodulator injections, including those with:

  • Allergies to Botox, Dysport, Xeomin, or their ingredients

  • An allergy to cow's milk protein

  • Pregnant or breastfeeding individuals

  • Neuromuscular conditions (e.g., Multiple sclerosis) or those with weakened muscles in the targeted area

  • Inflammation or infection in the treatment area

  • Drooping eyelids or sagging eyelid folds

  • Deep facial scars

  • Wrinkles that don’t smooth out when gently stretched

Potential Side Effects of Neuromodulator Injections

Most side effects are mild and temporary. Common injection-site reactions include:

  • Pain, swelling, or redness at the injection site

  • Bleeding or bruising

In rarer cases, more significant complications can occur, such as:

  • Infection

  • Eyelid ptosis (drooping eyelids) or asymmetry in the lower face if the toxin spreads to unintended muscles. These effects are temporary and last as long as the treatment’s effects.

Additional Resources