
Cosmic Injectables - Neuromodulators
(Botox, Dysport, Xeomin)
FDA-approved neuromodulators such as Botox, Dysport, and Xeomin are injectable treatments designed to temporarily reduce or eliminate moderate-to-severe dynamic wrinkles. These injectables are administered directly into the muscle beneath a wrinkle, relaxing the muscle and preventing it from contracting.
The injectables are derived from a neurotoxin produced by the bacterium Clostridium botulinum.
Applications for Neuromodulators
Medically, neuromodulators are used to treat conditions like migraines, TMJ (jaw clenching/grinding), excessive underarm sweating, cervical dystonia (which causes neck pain and abnormal head positioning), and muscle spasms.
Cosmetically, neuromodulator injections are commonly used to address:
Forehead wrinkles
Frown lines (between the brows)
Crow's feet
Nasal wrinkles
Neck bands

Injectable Procedure and Results
The neuromodulator is injected directly into the facial muscles causing wrinkles and lines, using a fine needle. While anesthesia is generally not required, some providers may numb the area with ice or topical numbing cream. Results are typically noticeable within a few days, and effects can last up to 4 months. Areas treated consistently may see longer-lasting results. It's important that injections are performed by qualified medical professionals.
Who Should Avoid Neuromodulator Treatment?
Certain individuals may not be suitable candidates for neuromodulator injections, including those with:
Allergies to Botox, Dysport, Xeomin, or their ingredients
An allergy to cow's milk protein
Pregnant or breastfeeding individuals
Neuromuscular conditions (e.g., Multiple sclerosis) or those with weakened muscles in the targeted area
Inflammation or infection in the treatment area
Drooping eyelids or sagging eyelid folds
Deep facial scars
Wrinkles that don’t smooth out when gently stretched
Potential Side Effects of Neuromodulator Injections
Most side effects are mild and temporary. Common injection-site reactions include:
Pain, swelling, or redness at the injection site
Bleeding or bruising
In rarer cases, more significant complications can occur, such as:
Infection
Eyelid ptosis (drooping eyelids) or asymmetry in the lower face if the toxin spreads to unintended muscles. These effects are temporary and last as long as the treatment’s effects.